Endocrinology: Cortisol, HPA, Adrenals

Lecture
Insert description here.
Lecturer

Arjen-Kars Boer

Date

March 26, 2025

Slides

13:30 - 15:15 - Clinical Endocrinology

Learning Outcomes

Principal Learning outcome:

  • Endocrinology is both a medical specialism dealing with diagnosing/ treatment of endocrine systems, and a basic science describing the endocrine physiology of endocrine organs.
  • The most important human processes are regulated by hormones
  • Laboratory hormone testing is essential to assess human endocrine systems, but the (dynamic) context is more important than the numeric results itself.
  • Interpretation by specialist like a clinical chemist-endocronologist is key for clinical decision making.

Lecture learning outcome:

Interpretation of endocrine laboratory testing is dependent on multiple factors, including: - Kinetics - Time of sampling - Matrix (blood versus saliva) - Exogeneous stimuli (eg dexamethasone, ynacthen, insulin)

Interpretation of endocrine Laboratory results related to: - Hypocortisolism - Hypercortisolism

Book Chapters

  • Human Metabolism: A Regulatory Perspective, Chapter 6
  • Lecture Slides